| 2023-09-08 19:00:00September 8, 2023 | Red Land vs Mechanicsburg | 30 - 49 | N/A |
| 2023-09-08 19:00:03September 8, 2023 | York vs Carlisle | 19:00:037:00 pm | N/A |
| 2023-09-08 19:00:10September 8, 2023 | Middletown vs Susquehanna Twp. | 13 - 28 | N/A |
| 2023-09-08 19:00:10September 8, 2023 | Dover vs Northern York | 19:00:107:00 pm | N/A |
| 2023-09-08 19:00:11September 8, 2023 | Palmyra vs Donegal | 19:00:117:00 pm | N/A |
| 2023-09-08 19:00:12September 8, 2023 | Newport vs Big Spring | 0 - 47 | N/A |
| 2023-09-08 19:00:12September 8, 2023 | Halifax vs Hancock | 19:00:127:00 pm | N/A |
| 2023-09-08 19:00:14September 8, 2023 | Boiling Springs vs Gettysburg | 19:00:147:00 pm | N/A |
| 2023-09-08 19:00:16September 8, 2023 | Juniata vs West Perry | 21 - 39 | N/A |
| 2023-09-08 19:00:18September 8, 2023 | State College vs Holidaysburg | 19:00:187:00 pm | N/A |
| 2023-09-08 19:00:20September 8, 2023 | Lower Dauphin vs Elizabethtown | 28 - 0 | N/A |
| 2023-09-08 19:00:20September 8, 2023 | Spring Ford vs Cumberland Valley | 63 - 17 | N/A |
| 2023-09-08 19:00:21September 8, 2023 | Tri-Valley vs Line Mountain | 23 - 14 | N/A |
| 2023-09-08 19:00:21September 8, 2023 | CD East vs Northeastern | 60 - 6 | N/A |
| 2023-09-08 19:00:23September 8, 2023 | Coatesville vs Central Dauphin | 13 - 35 | N/A |
| 2023-09-08 19:00:24September 8, 2023 | Milton Hershey vs East Pennsboro | 28 - 34 | N/A |
| 2023-09-08 19:00:24September 8, 2023 | J.P. McCaskey vs Cedar Cliff | 6 - 43 | N/A |
| 2023-09-08 19:00:32September 8, 2023 | Greencastle-Antrim vs Delone Catholic | 19:00:327:00 pm | N/A |
| 2023-09-08 19:00:33September 8, 2023 | Harrisburg vs Manheim Township | 19:00:337:00 pm | N/A |
| 2023-09-08 19:00:41September 8, 2023 | Upper Dauphin vs Camp Hill | 20 - 42 | N/A |
| 2023-09-08 19:00:43September 8, 2023 | Waynesboro vs Chambersburg | 20 - 40 | N/A |
| 2023-09-08 19:00:44September 8, 2023 | Wyomissing vs Trinity | 35 - 34 | N/A |
| 2023-09-08 19:00:46September 8, 2023 | Altoona vs Mifflin County | 35 - 0 | N/A |
| 2023-09-08 19:00:47September 8, 2023 | Dallastown vs Hershey | 19 - 35 | N/A |
| 2023-09-08 19:00:52September 8, 2023 | La Salle College vs Bishop McDevitt | 21 - 47 | N/A |
| 2023-09-08 19:00:52September 8, 2023 | Spring Grove vs Shippensburg | 6 - 14 | N/A |
| 2023-09-08 19:00:52September 8, 2023 | Susquenita vs Schuylkill Valley | 14 - 48 | N/A |
| 2023-09-08 19:00:55September 8, 2023 | James Buchanan vs Biglerville | 19:00:557:00 pm | N/A |
| 2023-09-09 13:00:10September 9, 2023 | Steel-High vs West Catholic | 13:00:101:00 pm | N/A |
